Wednesday, November 27, 2019

Photography Is A Technique Of Producing Permanent Images On Sensitized

Photography is a technique of producing permanent images on sensitized surfaces by means of the photochemical action of light or other forms of radiant energy. In today's society, photography plays important roles as an information medium, as a tool in science and technology, and as an art form, and it is also a popular hobby. It is essential at every level of business and industry, being used in advertising, documentation, photojournalism, and many other ways. Scientific research, ranging from the study of outer space to the study of the world of subatomic particles, relies heavily on photography as a tool. In the 19th century, photography was the domain of a few professionals because it required large cameras and glass photographic plates. During the first decades of the 20th century, however, with the introduction of roll film and the box camera, it came within the reach of the public as a whole. Today the industry offers amateur and professional photographers a large variety of cameras and accessories. See also Motion Picture. The Camera and Its Accessories Modern cameras operate on the basic principle of the camera obscura (see Historical Development, below). Light passing through a tiny hole, or aperture, into an otherwise lightproof box casts an image on the surface opposite the aperture. The addition of a lens sharpens the image, and film makes possible a fixed, reproducible image. The camera is the mechanism by which film can be exposed in a controlled manner. Although they differ in structural details, modern cameras consist of four basic components: body, shutter, diaphragm, and lens. Located in the body is a lightproof chamber in which film is held and exposed. Also in the body, located opposite the film and behind the lens, are the diaphragm and shutter. The lens, which is affixed to the front of the body, is actually a grouping of optical glass lenses. Housed in a metal ring or cylinder, it allows the photographer to focus an image on the film. The lens may be fixed in place or set in a movable mount. Objects located at variou s distances from the camera can be brought into sharp focus by adjusting the distance between the lens and the film. The diaphragm, a circular aperture behind the lens, operates in conjunction with the shutter to admit light into the lighttight chamber. This opening may be fixed, as in many amateur cameras, or it may be adjustable. Adjustable diaphragms are composed of overlapping strips of metal or plastic that, when spread apart, form an opening of the same diameter as the lens; when meshed together, they form a small opening behind the center of the lens. The aperture openings correspond to numerical settings, called f-stops, on the camera or the lens. The shutter, a spring-activated mechanical device, keeps light from entering the camera except during the interval of exposure. Most modern cameras have focal-plane or leaf shutters. Some older amateur cameras use a drop-blade shutter, consisting of a hinged piece that, when released, pulls across the diaphragm opening and exposes the film for about 1/30th of a second. In the leaf shutter, at the moment of exposure, a cluster of meshed blades springs apart to uncover the full lens aperture and then springs shut. The focal-plane shutter consists of a black shade with a variable-size slit across its width. When released, the shade moves quickly across the film, exposing it progressively as the slit moves. Most modern cameras also have some sort of viewing system or viewfinder to enable the photographer to see, through the lens of the camera, the scene being photographed. Single-lens reflex cameras all incorporate this design feature, and almost all general-use cameras have some form of focusing system as well as a film-advance mechanism. Camera Designs Cameras come in a variety of configurations and sizes. The first cameras, ?pinhole? cameras, had no lens. The flow of light was controlled simply by blocking the pinhole. The first camera in general use, the box camera, consists of a wooden or plastic box with a simple lens and a drop-blade shutter at one end and a holder for roll film at the other. The box camera is equipped with a simple viewfinder that shows the extent of the picture area. Some

Sunday, November 24, 2019

Government of France

Government of France The government of France is a semi-presidential system based on the French Constitution of the fifth Republic, in which the nation declares itself to be "an indivisible, secular, democratic, and social Republic". The constitution provides for a separation of powers and proclaims France's "attachment to the Rights of Man and the principles of national sovereignty as defined by the Declaration of 1789."The national government of France is divided into an executive, a legislative and a judicial branch. The President has a degree of direct executive power, but most executive power resides in his appointee, the Prime Minister. The President's choice for Prime Minister must have the confidence of the National Assembly, the lower house of Parliament; also the Prime Minister is always from the majority party in that house.Parliament comprises the National Assembly and the Senate. It passes statutes and votes on the budget; it controls the action of the executive through formal questioning on the floor of the houses of Parliament and by establishing commissions of enquiry.President Wilson and President Poincare of FranceThe constitutionality of the statutes is checked by the Constitutional Council, members of which are appointed by the President of the Republic, the President of the National Assembly, and the President of the Senate. Former Presidents of the Republic also are members of the Council.The independent judiciary is based on a civil law system which evolved from the Napoleonic code. It is divided into the judicial branch (dealing with civil law and criminal law) and the administrative branch (dealing with appeals against executive decisions), each with their own independent supreme court, the courts of cassation. The French government includes various bodies that check abuses of power and independent agencies.France is a unitary state. However, the various legal subdivisionsthe r ©gions, d ©partements and communeshave various attributions, and the nationa l government...

Thursday, November 21, 2019

Research methods Assignment Example | Topics and Well Written Essays - 2250 words

Research methods - Assignment Example The USASuperCars signed a new contract, which would allow it to sell its batch of 27 luxury cars to various customers around the globe, primarily in the UK, Japan, Canada, South Africa and the USA. The contract states that the selling price of the products are fixed and in local currencies at the exchange rates at the time of the delivery. In the real economic world set up, the exchange rate is marked with high level of precariousness. Therefore, one, particularly a businessman, cannot simply overlook the idea about the linked benefits and risks to the stated contract. In this event, the HSBC offered to pay a sure sum of $2,150,000 in return for revenue in local currencies. It is at this point that the work at hand seeks to come up with a decision whether to accept or reject the offer by weighing up the associated benefits and risks. In addition, in the event that the HSBC’s offer is accepted, finding for which payment schedule is better based on the point of view of USASuperC ars and HSBC, searching for other potential risks HSBC will be exposed to, and finally understanding the measures that can be taken in order to at least minimize the exchange rate risk beyond converting all currencies into dollars. Profit analysis for USASuperCars is vital for this case, prior to deciding which payment option is necessary provided that the offer of HSBC is accepted. Recommendations are provided, which are associated with HSBC’s offer. The justification behind the profit analysis is based on the information of the worldwide order, the quantity and the selling price of luxury cars in the local currencies. To ensure the information about exchange rate is properly considered, the mean and standard deviation rate for converting each currency into dollars are included based on the historical data. Based on the assumption that the rates are normally distributed and independent with each other, the profit has the assumption that it is normally distributed as well. As

Wednesday, November 20, 2019

Impact of External Environment on Apple Operations Essay

Impact of External Environment on Apple Operations - Essay Example On the other hand, the company internal factors that arise from external effects include strong brand name, diversified product portfolio, strong management team and mergers. To remain competitive and address the weaknesses of the poor relationship with the major competitor, it is imperative for the company to form more mergers with a large company such as Dell. In the same way, the company should utilize the available market opportunities by advertising its products through social sites such as facebook and twitter. This is in addition to establishing more sales outlets in the developing countries. One of the vital strategies that firms adapt to face off stiff competition in the contemporary business arena is the use of well-designed marketing plan that takes into consideration the effects of external environment on the operations of a firm. One of the companies that have attained a competitive advantage due to its effective marketing strategies is Apple Incorporation. Apple Inc. is an international company that deals with marketing and designing of computers hardware and software as well as household electronics products. Earlier on, the company was referred to as Apple computer incorporation (Adam, 2012). Apple Inc. which is headquartered in the US is well known for the quality and high-tech brands that have revolutionized communication. This marketing audit analyzes the impact of external environment on Apple operations by reflecting the current market situation of the company.The company is focused on becoming the market leader in the electronic and technology industry glob ally. According to the former chief executive officer, Mr. Steve Jobs, computers provided by Apple should be on every desk in the next 8 years. Apple Company will persist in offering innovative and revolutionized brands to its customer to meet their short term and long term demands.  

Sunday, November 17, 2019

Maria Montessori Language Arts Rationale Essay Example | Topics and Well Written Essays - 750 words

Maria Montessori Language Arts Rationale - Essay Example A child learns to listen by hearing the various sounds that the adults around him and also learns to speak by imitating the various sounds that the adults make around him.as Maria Montessori said: There are three main areas where children are prepared for reading and writing. The first is physical skills where a child learns to balance using their hands and coordination of the hand and the eye works. The child also learns to concentrate and focus on the practical issues of life, recognizing sizes and shapes, working with paints, crayons, pencils and practice in talking. The second skill that a child learns is the mental skills where the child learns to absorb and how to use language and how to learn the sounds that each letter of the alphabet makes. This can be made easy by playing games to break up words into sounds (Montessori, 2010). The third skills are the social skills where people living in homes sit down and have conversations instead of watching the television or using the computer to learn language. A directress would know that a child is ready to learn a sound if they try to repeat what has been said to them by an adult around them. The child will also be making sounds on their own that they have heard before. Sounds are taught to children by repeating the sounds over and over until the child is able to differentiate it from other sounds. In learning the different sounds, he child is taught the various sounds of the different letters of the alphabet. There are different rules for the letters and children are very receptive towards rules. Therefore, they are first taught the rules than the different sounds of the letters of the alphabet (Montessori, 1909). The child is taught the phonetic words first and once they have mastered the phonetic part of the alphabets, they are next taught the non-phonetic part of the language where there are no rules whatsoever. A child learns to blend sounds by learning the individual

Friday, November 15, 2019

Types of Waste

Types of Waste Waste is known as a matter which current users have no purpose of, or it is known as a matter which can be harmful to humans, animals or the environment. Waste can be divided into two categories, general and hazardous waste. General waste is waste that does not harm humans, animals or the environment. For example household waste, garden waste, building rubble, dry industrial and commercial waste. Hazardous waste is more likely to cause danger to humans, animals and the environment. This waste is based on the chemical reactivity, explosives, corrosive and radioactive. Waste Found In the Community of Edenvale There is many different waste found in the community which affect the community. The types of waste found in my community are agricultural waste which comes from animal products and the production of crops. This waste can be recycled. Biodegradable waste is a type of waste that will go back into the soil and nature. This may include garden waste, animal waste, fruit and vegetable leftovers. This waste can be composted. Garden waste is known as grass clippings, weeds, tree branches and this can all be composted. Bulk waste is large waste, such as broken appliances, furniture and outer parts. Almost all of this waste can be reused or recycled. Trade waste is waste is generated by shops, offices, or commercial places. Construction waste is found on residential premises. This waste includes batteries, empty paint and pesticide containers. Some of the household waste is recyclable. Industrial waste is waste that comes from industrial and manufacturing processes. Some of this waste is haza rdous. Intuitional waste is found in schools, hospitals, research institutions and public buildings. Medical waste is known as any solid or liquid waste which is generated in treatments. The Waste plan in my Community In my community the waste management plan for households is that waste is collected once a week. Businesses are different and get waste removed twice a week depending on how much waste is generated. Industrial waste is also collected once a week. It has been working effectively because the municipality has had no complaints and customers are happy with the system. The community also stays clean by means of the council collecting waste around bins so that the community will stay clean. Hazardous waste containers are also being provided and specialized companies deal with this waste. People that dump illegally get high fines. Public roads are being taken care of by litter being picked up by services five times a week. In the CBD litter gets picked up seven days a week. Free standing pole bins get emptied daily. Informal Settlements around my Community Some informal settlements where waste is not managed well is in the CBD, Hillbrow, New Town, Alexandra Township, and Jeppestown. The pollution comes in the form of dust from gravel roads, lack of clean running water, lack of regular refuse removal, broken and non-maintained sewerage pipes, absence of toilet facilities and ignorant littering. Due to the overcrowding of the informal settlements with migrants who are unemployed, and are not able to pay housing rent leads to a decay of flats and houses. In Alexandra some people still use the bucket system which increases the contamination from sewerage in the environment, and some people can get a wide range of illnesses. The organic waste attracts rodents and insects infestations. Poverty and lack of knowledge in these areas lead to littering, overflow of broken sewerage systems and unmanaged waste. A waste management plan for the informal settlements is that refuse is removed twice a week by means of bulk containers and street hawkers are issued with refuse bags weekly. â€Å"The metropolitan council wants a waste disposal strategy; identification of waste disposal sites, establishments, operation and control of waste disposal sites.† The community water supply and sanitation programs aims to ensure all South Africans have access to clean water. The metropolitan also wants to prevent invasion of industrial sites. Some solutions that can help reduce waste are: Waste Avoidance, Prevention and Minimization: system to ensure the appropriate design promotion, optimizing operating procedures and good house keeping for all waste generating processes. Forecasting potential situations in which accidents and spills can cause unscheduled waste emissions. Recovering, Recycling and Reuse: Reduction in the waste stream. Recycle materials such as taxes on waste or subsides for waste cycling, and also extraction and utilization of landfill gas. Treatment and handling: Ensuring that waste is appropriately treated and processed to their disposal in accordance with laws, regulations and guidelines. Storage and Final Disposal: Timely identification investigation and construction of environmentally and socially acceptable waste disposal facilities. New innovative ways of managing waste in disadvantaged communities are required. We can move towards collection by paying people to collect litter and involve the community in programs. We can improve the awareness to the public with regard to waste. Allow people living in informal settlements to regain their dignity by providing sustainable, affordable sanitation. Polokwane Declaration The aim of the Polokwane Declaration is to reduce waste by 50 % respectively by 2012 and have a plan for zero waste by 2022. In order to achieve their goals they must engage more closely in a realistic and practical manner. Conclusion In Gauteng waste management is lacking it appears there has been an increase in waste per year between 1998 and 2003. It also appears that Polokwane Declaration of zero waste remains optimistic. Hazardous waste has decreased as a result of improvement in industrial activities. Recycling initiatives are being adopted and are successful. The importance of the public awareness of waste and recycling should be made aware and action plans formulated.

Tuesday, November 12, 2019

Internship in Public Relations Department of an Advertising Agency Essay

Section I Introduction 1.1 Background Internship is one of the essential parts required for the completion of MBA program. It is to provide first hand exposure to the students about the real work scenarios in business organizations. It allows students to imply their theoretical knowledge in the real workplace by enhancing their ability and confidence level in the dynamic business world. Besides, one of the objectives of this program is to enhance student’s interpersonal, communication, report writing skills as well as presentation skills and to understand different viewpoint of the staff and the customer of the organization. 1.2 Objective of the internship The objectives of my internship at Prisma Advertising agency are: To fulfill the requirement of MBA program of Pokhara University. To understand importance Public Relations in corporate world. To understand how public relations enhances brand image. To comprehend successful events. 1.3 Placement For the purpose of internship, the trainee was allowed to perform internship in the organization where she was actively working for past two years. The organization is an advertising agency named Prisma Advertising located in Kalikastha, Kathmandu. The internee had been working in Public Relations Department (PR) as an Executive. 1.4 Expected Learning Experiencing the real life working environment Expand the boundaries of theoretical learning Develop better public relation skills with media as well as in corporate sector Section II Industry and Organization Profile 2.1 Industry Profile There are no records of any kind that tell us about the origin and history of Nepali advertisements. The earliest form of advertising may thus be taken as the trumpet blowing tradition of kings and maharajas to disperse royal messages. The advent of Mass Communication in Nepal can be said to have been through such official proclamations, which were usually accompanied by the use of musical instruments like drums or trumpets. The age-old oral tradition of promotion by vendors selling their wares in the market can also be taken as another early form of advertising. With the national daily  Gorkhapatra churning out advertisements on a regular basis, the advertising sector caught momentum, and the next major development came in the form of an advertising agency, Laxman Upadhaya’s Nepal Advertisers. The main objective of the agency was to publish flashy and attractive advertisements in the print media. Three years later, following in the footsteps of Upadhaya, Keshav Lamichane started Nepal Printing and Advertising Agency owned by Keshav Lamichane. This agency held the accounts of prime clients like Janakpur Cigarette Factory, Royal Nepal Airlines Corporation and Nepal Bank Limited. 2.2 Prisma Advertising Profile Prisma Advertising is the franchisee of Mathew and Ogilvy in Nepal. It is one of the most creative agencies which established in 1991. It is a full service office with team of 47 people which has been growing as creative leader and 360 degree brand stewardship. It provides wide range of services from media, branding, and sales promotion to advertisement. They continuously thrive to provide creative products by giving a consumer touch to what they deliver, also offer fully integrated marketing communication solutions as well as focus on building brand relationship with the consumers. It has been awarded as The Best Agency of the Year 2004-05, 2005-06, 2006-07 & 2007-2008 (four years in a row). In addition to it also has won the only international advertising award for Nepal – â€Å"Bell Ringer 2000† from Johnson &Johnson, USA. Prisma approach to communication: These activities are part of the prisma advertisement agency which is provided to the clients according to the promotion they required for their products and services. 2.3 Importance of Public Relation Department Why does Brand or an Organization need a Public Relation Department? Unless one is a celebrity, good public relation just does not happen on its own. It takes lots of skill and consistent hard work, over a period of time. It’s part art, part science and when practiced correctly the results can be very rewarding. Here are few reasons why Public Relations is important: Media coverage increases credibility Paid advertising increases name recognition; media relations increases credibility. When people read a story about the excellence of a particular organization in a newspaper or see a story praising the company on television, they are much more likely to have a favorable opinion of that particular organization. Media coverage helps to attract â€Å"quality† prospects  Because a public relations increases credibility, it helps to attract those who want the best. When people have heard of the organization or brand and have a favorable impression of it, it is easier to attract and hold their attention while the organization or the brand tell their story. Media coverage makes you a player  Coverage in important publications or on TV can make the organization or brand look much larger than it is. Public relations help to avoid price competition  If people believe that the particular brand is the best, they will understand why it is worth paying the price. A public relations program stretches the marketing budget  Because the media does not charge for news coverage, the relative cost of a good program is a lot less than for paid media or a direct mail campaign. Best way to launch a brand  Public relations are also considered by many as the best way to launch a brand or new product. When something is new the media often will write about it because of its news value. Section III Critical Analysis of Job Performed 3.1 Function of Public Relation Department PR Department functions to maintain and enhance mutual understanding/relationship between its clients and public. The core responsibility of the PR Department is to build and protect the brand. PR communicates client’s views, objectives and purposes to the general mass and at the same time monitors feedback and correcting the public attitudes/ reactions. For this, department focuses on major areas: Crisis Management: To avoid any crisis and its adverse effects to its clients, the PR Department prepares press releases and makes them public through media vehicle. Corporate Social Responsibility (CSR): Also known as corporate responsibility, corporate citizenship, responsible business and corporate social performance that forms of corporate self-regulation integrated into a business model. To fulfill these responsibilities the company’s want to conduct events, and any such social events are organized for the client by this department. For example: charity program. Further, they also create social awareness for NGOs and INGOs and other organizations working for the welfare of the society at discount rates. Event Management: Various events such as press conference, product launching events etc. are organized either to provide new information or introduce a new product. In such events, various media houses, guests are invited and are provide with the press release which gives details about the event. Monitoring and tracking current scenario: Either it be country’s current happenings or competitor’s activities, PR Department tracks the entire essential data with the help of media and reports to the internal staff members as well as the client in daily basis as well as a monthly reports. 3.2 Activities Performed The internee was part of a PR Team and there were five members in this team. Public Relation Head, Senior Public Relation Supervisor, Copy Writer and PR Executives are the designations of this team. The internee was working under direct assistance of Senior Public Relation Supervisor. Each team members  had their specific task that they were assigned to and those were mentioned in their job description. Following were the job assigned to the intern. 1. Everyday internee had to make a daily update on country’s news update regarding political, business and social happenings and send it to the clients. 2. Track on competitor’s activities like press ad, news and send it to respective clients. 3. Make Share of Expense (SOE) respective to the competitor’s and send it to clients on monthly basis. 4. Make regular interactions with media as well as clients to enhance better public relation. 5. Make press releases, news articles on client’s activities and send it to media for the coverage. 6. Organized events like Press Conferences, Formal meetings with government bodies, and Cocktail parties as per the clients need. 7. Crisis management of the clients. Bajaj Pulsar 200 NS Launch, Coca-Cola Inter-School National Football Tournament, Coca-Cola ‘Live Positively ‘and Western Union’s collaboration with Mercy Corps to empower 1200 women to be financially literate were some of the major events organized as an internee under PR Department. The major task of the PR Department during these events was to highlight the program as much as possible with the help of media as well as word of mouth publicity. Few of the coverage of these events are attached below. Coverage of the Events Bajaj Pulsar 200 NS launch Coca-Cola Inter-School National Football Tournament Coca-Cola ‘Live Positively’ Western Union’s collaboration with Mercy Corps Activities Performed Working as an intern in PR Department, internee had to face several crisis situations where various brand reputation damaging news were covered by  newspapers and television. To tackle with those situations, crisis management was done. Few examples of Crisis Management are as follows: Nepal Samachar Patra and Sagarmatha Television were continuously showcasing various news regarding faulty products of Bottler’s Nepal Limited. To surpass those negative news, internee with the PR team had undergone the crisis management by flowing the positive news of the company in The Kathmandu Post. This is a technique where PR people do not counter the negative news directly but highlights the positive aspect of the company, person or the brand to put the positive news in the top of the publics mind. Negative News covered by Nepal Samachar Patra Positive News published in The Kathmandu Post 3.3 Public Relation Department Analysis As an internee under PR Department of an advertising agency, 3.4 Problem Identification and Solution Alternatives As every best effort does have a loop hole, PR Department also has to face certain problems at times.

Sunday, November 10, 2019

Nitric Oxide Therapy in infants with pulmonary hypertension

The benefits of nitrogen oxide (NO) therapy as used in the treatment of infants with persistent pulmonary hypertension (PPHN) can be best appreciated if the reader is familiar with the pathophysiology of PPHN and the previous methods used in treating the disease. The function of NO has evolved in the minds of the scientific community from being a mere noxious gas emitted by vehicles to a wonder compound in the field of medicine. In the area of pulmonology, its vasodilatory effect in the blood vessels is now being used to assist PPHN patients in rerouting blood flow in infants whose blood circulation fails to shift from fetal to normal circulation.Such nature of the compound, being the main ingredient in NO therapy allows for a less invasive procedure which in effect reduces risks of complications during and after treatments, expected in previous treatment methods. This reduced risks account for the relatively more cost-effective character of NO therapy as a treatment method in PPHN p atients.There is not much use for the lungs during the fetal life. At such stage, the function of the lungs is carried out by the placenta through the umbilical cord. Fetal life is characterized by a high pulmonary vascular resistance (PVR) with pulmonary blood flow being restricted to a less than 10% lung-directed cardiac output. Blood vessels that connect the heart and the lungs are constricted, sending the circulating blood back to the heart through the ductus arteriosus, a blood vessel that functions only in fetuses. In other words, the lungs in the fetal stage are bypassed.At birth, when the lungs finally assume the function of gas exchange, the PVR decreases, allowing for an increase in pulmonary blood flow. The blood vessel that is previously constricted, favoring blood flow to the ductus arteriosus is now relaxed, simultaneously with the permanent closure of the ductus arteriosus. This happens as the lungs become ventilated and the alveolar oxygen tension is increased.Persis tent Pulmonary Hypertansion occurs when at birth, the lung circulation fails to achieve the normal drop in PVR, preventing the transition from fetal to newborn circulation. This failure results in the continuous functioning of the ductus arteriosus which impairs the flow of blood from the heart to the lungs and limits the amount of oxygen that can be picked up by the blood to be delivered to the different parts of the body. The blood that flows back to the heart remains in an unoxygenated state which could lead to the development of refractory hypoxemia, respiratory distress and acidosis.It is only in 1987 when nitric oxide (NO) was recognized as a key endothelial-derived vasodilator molecule. From then, research has been expanded to establish the role of NO throughout the body, and to discover its therapeutic potential.   To appreciate the effects of NO in alleviating pulmonary hypertension, it is important to gain understanding of its chemistry and mechanism of action.Nitric Oxi de is a gaseous compound that rapidly diffuses across membranes and has a single unpaired electron. This explains its high reactivity, especially to Hemoglobin (Hb) in the blood. This nature of the compound accounts for its noted biological significance. It has been discovered to function as stimulant in the release of hormones; as neurotransmitter; a significant participant in the magnification of synaptic actions and learning processes; and an inhibitor in platelet aggregation, which makes it a marvel in the field of cardiology. In the field of pulmonology, nitric oxide is valued for its vasodilatory effect in the blood vessels.This effect can be explained by the mechanism involving the compound's diffusion from the vascular endothelial cells to the subjacent smooth muscles of the pulmonary vessels. From here, NO activates the enzyme guanylate cyclase to change conformation to promote smooth muscle relaxation by converting GTP to cGMP.   This vasodilatory effect signals the mech anism to modulate blood flow and vascular tone.Given the mechanism of action, it is easy to surmise how NO can be utilized as a therapeutic agent in the management of blood-vessel-related diseases such as those related to the heart (hypertension), the reproductive system(erectile dysfunction) and in this case, the lungs (Persistent Pulmonary Hypertension in infants (PPHN)).Before NO, treatments used in infant PPHN are hyperventilation, continuous infusion of alkali, tube vasodilation and vasodilator drugs. A study on the effects of these various treatments was done by Ellington, Jr., et. al., (2001) showing no specific therapy clearly associated with the reduction in mortality in infants. In determining whether therapies were equivalent, the study showed that hyperventilation reduced the risk of extracorporeal membrane oxygenation (ECMO) with no oxygen increase at 28 days, while alkali infusion increased the use of ECMO as well as an increase in the use of oxygen at 28 days (Ellingt on, Jr., et. al., 2001). ECMO is a highly invasive procedure that requires major surgery, performed in serious cases of PPHN when patients fail to respond to treatments.It is only after post-lab studies were able to identify the role of NO-cGMP signaling in the regulation of lung circulation that NO therapy was developed for PPHN (Channick, R., et. al., 1994). Like previous treatment methods, NO therapy improves oxygenation as well as reduces the risk of ECMO in infants with PPHN (Oliveira, et. al., 2000). But because nitric oxide is capable of acting on its own upon inhalation to relax the blood vessels and improve circulation, it is considered as a less invasive procedure in the management of infants with PPHN compared to the previous treatments mentioned in the preceding paragraphs.The efficiency of the treatment procedure can be determined by observing its effect on the patient's ventilation and blood flow, which is a determinant of the efficiency of transpulmonary oxygenation a nd partial pressure of oxygen in the systemic arterial blood (Ichinose, et. al., 2004). NO therapy enhances the mechanism by which blood flow is redistributed toward regions in the lungs with better ventilation and higher intra-alveolar partial pressure of oxygen (Ichinose, et. al., 2004).Other treatments used in the management of PPHN such as tube ventilation, alkalosis and intravenous vasodilators were shown to be effective in ameliorating pulmonary hypertension in some infants, but in many instances, it does not, as ECMO almost always becomes a necessity in saving the life of the infants (Ichinose, et. al., 2004). A type of hyperventilation has been proven not to increase the risk of ECMO, but unlike NO-therapy (Ellington, Jr., et. al., 2001), it is invasive as to require a tube inserted inside the infant's trachea.In patients with moderate PPHN, there is an improvement in arterial p a O 2, reduced necessity of ventilator support and low risk of progression to severe PPHN (Sadiq, et. al., 2003) and this, without the risk of increasing the incidence of adverse outcomes when the age of 1 year is reached (Clark, et. al. 2003). Inhaled NO is able to rapidly increase the arterial oxygen tension and increase the blood flow in the lungs without causing systemic hypotension (Roberts, 1992; Kinsella, 1992). No apparent increase in morbidity has been shown after one year of treatment with NO (Aparna and Hoskote, 2008). For high-risk infants with PPHN, inhaled NO has been found to lessen the risk of pulmonary hypertensive crisis (PHTC) after congenital heart surgery (Miller, et. al. 2000).Studies on the role of NO in the management of PPHM show that while it is therapeutic, it also prevents the occurrence of chronic lung disease which affects morbidity. Vascular cell proliferation and pulmonary vascular disease have been shown to decrease with NO in the newborn (Roberts, et. al., 1995). In addition, while NO treatment can be more costly, it is the most cost-effective among other methods because of the reduced need for ECMO (Angus, et. al. 2003). For these reasons, it is understandable why NO therapy seems to have taken over in the area of PPHN treatment.ReferencesAngus DC, Clermont G, Watson RS, et al. (2003). Cost-effectiveness of inhaled nitric oxide in the treatment of neonatal respiratory failure in the United States. Pediatrics. 112, 1351–1360.Aparna U., Hoskote, MD., et. al. (2008). Airway function in infants treated with inhaled nitric oxide for persistent pulmonary hypertension. Pediatr Pulmonol. 43, 224-235.Channick R, Hoch R, Newhart J, et al. (1994). Improvement in pulmonary hypertension and hypoxemia during nitric oxide inhalation in a patient with end-stage pulmonary fibrosis. Am J Respir Crit Care Med. 149, 811-814Clark, RH., Huckaby, JL., et. al. (2003). Low-Dose Nitric Oxide Therapy for Persistent Pulmonary Hypertension: 1-Year Follow-up. Journal of Perinatology. 23, 300.  Ellington Jr, Marty, O'Reilly, et. al. (2001). C hild Health Status, Neurodevelopmental Outcome, and Parental Satisfaction in a Randomized, Controlled Trial of Nitric Oxide for Persistent Pulmonary Hypertension of the Newborn. Pediatrics,107.Ichinose F, Roberts JD, et.al. (2004). A Selective Pulmonary Vasodilator: Current Uses and Therapeutic Potential. Circulation. 109, 3106-3111. Kinsella JP, Neish SR, Shaffer E, et al. (1992). Low-dose inhalation nitric oxide in persistent pulmonary hypertension of the newborn. Lancet.   340, 819–820.Miller O, Tang SW, et. al. (2000) Inhaled nitric oxide and prevention of pulmonary hypertension after congenital heart surgery: A randomised double-blind study. The Lancet. 356: 9240, 1464.Oliveira cac, et. al. (2000). Inhaled Nitric oxide in the management of persistent pulmonary hypertension of the newborn: a meta-analysis. Rev. Hosp. Clin. Fac. Med. S., 55 (4): 145-154, 2000Roberts JD Jr, Polaner DM, Lang P, et al. (1992). Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet. 340, 818–819.Roberts JD Jr, Roberts CT, Jones RC, et al. (1995). Continuous nitric oxide inhalation reduces pulmonary arterial structural changes, right ventricular hypertrophy, and growth retardation in the hypoxic newborn rat. Circ Res. 76, 215-222.  Sadiq HF, Mantych G, et. al. (2003). Inhaled Nitric Oxide in the Treatment of Moderate Persistent Pulmonary Hypertension of the Newborn: A Randomized Controlled, Multicenter Trial. Journal of Perinatology.   23, (2).98

Friday, November 8, 2019

Home Treatment for Jellyfish and Man of War Stings

Home Treatment for Jellyfish and Man of War Stings You can apply common household chemistry to treat jellyfish and Portuguese man-of-war stings. However, jellyfish and Portuguese man-of-war are two different animals. Heres a look at how to tell them apart and how the chemistry of treating the stings differs depending on what stung you. Key Takeaways: Jellyfish and Portuguese Man-of-War Stings A jellyfish can sting you even if its dead.Vinegar, ammonia, meat tenderizer, or heat can inactivate the toxin in jellyfish venom. However, if there is a risk a sting is from a Portuguese man-of-war, using a chemical can cause all of the stinging cells to fire at once and worsen the injury.Another method of treating a sting is to lift off the tentacle (like with a credit card or seashell) and rinse the area with water.An antihistamine can help reduce allergic response. Hydrocortisone can relieve inflammation. An over-the-counter pain reliever can help reduce pain. Dont Make the Sting Worse Do you know what to do if you or someone youre with finds a jellyfish or is stung by one? You should know the answer to these questions before you go to the beach since an encounter with a jellyfish can be a painful or possibly lethal experience. As a matter of practical chemistry, your biggest risk from a jellyfish or Portuguese man-of-war sting may come from improper first aid intended to deal with the venom, so pay attention... What Should You Do If You See a Jellyfish? Best Answer: Leave it alone. If its in the water, get away from it. If its on the beach and you need to walk around it, walk above it (dune side) rather than below it (surf side), since it may be trailing tentacles. Keep in mind a jellyfish does not need to be alive in order to sting you. Detached tentacles are capable of stinging and releasing venom for several weeks. Other Answer: It depends what kind of jellyfish it is. I realize if it looks like floating jelly, its considered a jellyfish, but there are different types of jellyfish and also animals that look like jellyfish but are something else entirely. Not all jellyfish can hurt you. Some jellyfish are either nonvenomous or else their stinging cells cant penetrate your skin. What do you do when you see one of these jellyfish? If you are a kid, youll probably pick it up and throw it at another kid (unless its alive, then be kind and let it be). Most parts of the world have nonvenomous jellyfish. They tend to be easy to spot. Its the ones you dont see that present the biggest threat. Many jellyfish are transparent (but glow under a black light). You probably wont see them in the water, so if you are stung, you wont know exactly what got you. If you see a jellyfish and dont know what type it is, treat it like a venomous species and get away from it. How Do I Treat a Jellyfish Sting? Answer: If you know the victim is allergic to insect stings, seek medical attention immediately. People who are allergic to bees and wasps may experience a dangerous allergic reaction to a jellyfish sting. Otherwise, act quickly and calmly to remove the tentacles, stop the stinging, and deactivate any toxin. Here is where people get confused because the best steps to take depend on what type of animal caused the sting. Use these good basic strategies, especially if you dont know what caused the sting: Get out of the water. Its easier to deal with the sting, and it takes drowning out of the equation.Rinse the affected area with seawater. Do not use fresh water. Fresh water will cause any stinging cells that havent fired (called nematocysts) to do so and release their venom, possibly worsening the situation. Do not rub sand on the area (same reason).If you see any tentacles, carefully lift them off the skin and remove them with a stick, shell, credit card, or towel (just not your bare hand). They will stick to swimwear, so use caution touching clothing.Keep an eye on the victim. If you see any signs of an allergic reaction, call 911 immediately. Symptoms could include difficulty breathing, nausea, or dizziness. Some redness and swelling is normal, but if it spreads outward from the sting or if you see hives on other parts of the body, that could indicate an allergic response. If you suspect a reaction, do not hesitate to seek medical attention.Now, if you are sure the sting is from a jellyfish and not a Portuguese man-of-war (not a true jellyfish) or any other animal, you can use chemistry to your advantage to inactivate the toxin, which is a protein. (Technically, the venom tends to be a mixture of polypeptides and proteins including catecholamines, histamine, hyaluronidase, fibrolysins, kinins, phospholipases, and assorted toxins). How do you inactivate proteins? You can change the temperature or acidity by applying heat or an acid or base, such as vinegar or baking soda or diluted ammonia, or even an enzyme, such as the papain found in papaya and meat tenderizer. However, chemicals may cause the stinging cells to fire, which is bad news for someone allergic to jellyfish toxin or anyone stung by a Portuguese man-of-war. If you do not know what caused the sting, or if you suspect it is from a Portuguese man-of-war, do not apply fresh water or any chemical. Your best course of action is to apply heat to the affected area since it penetrates the skin and inacti vates the toxin without causing more venom to be injected. Also, heat quickly helps alleviate the pain of the sting. Hot seawater is great, but if you dont have that handy, use any warmed object. Some people carry aloe vera gel, Benadryl (diphenhydramine) cream, or hydrocortisone cream. Im not sure how effective the aloe is, but Benadryl is an antihistamine, which may help limit an allergic response to the sting. Hydrocortisone can help reduce inflammation. If you seek medical attention and used Benadryl or hydrocortisone, be sure to alert the medical professionals. Acetaminophen, aspirin, or ibuprofen are commonly used to relieve pain.

Wednesday, November 6, 2019

Pet Overpopulation & The Importance of Spaying & Neutering essays

Pet Overpopulation & The Importance of Spaying & Neutering essays I constantly see dead dogs lying on the side of the road, and others roaming the streets. The ones roaming havent met their fate yet, but it may only be one car or a truck away; and the same holds true for cats. It amazes me how much people want to have a pet, and once they do they forget about taking care of them. They seem to think that the animals can fend for themselves, and they just turn them loose. They are irresponsible of their safety, and their care; this includes spaying and neutering. When pets are free to roam, they are free to breed. And, what happens to the product of all of this free breeding? These unwanted animals are crowding the shelters and it makes me very sad, and angry. Sure, they are out of harms way with a roof over their heads, and food in their stomachs, but they are unloved and unwanted. There are so many that wont be adopted, because there are just too many of them! Unfortunately the alternative is to humanely put them to sleep. I had the misfortune of handling a situation that got out of control. A situation that my dad started when he rescued a litter of abandoned kittens. His neighbors moved and left the kittens behind, and his kind heart took over. Unfortunately he didnt have the insight to think about the future, and what was going to happen down the road. All he thought about were hungry kittens that needed to be taken care of. My dad lives on a fixed income, and he couldnt afford to get 6 cats spayed and neutered, he could barely afford to feed them. Im not even sure it crossed his mind. But the kittens grew up, and they started reproducing. Litter after litter, until there were 12 cats, then they reproduced, and so on. Two years later there were 24 cats, and there would have been more except a few litters died. Looking back on it now, it was probably a blessing. A few of the adults wandered off and never returned, but in the end, there was ...

Sunday, November 3, 2019

Module Questions Law Coursework Example | Topics and Well Written Essays - 750 words

Module Questions Law - Coursework Example Assignment 1-2 Q. In Edward Sutherland's definition of crime, there are three areas that form the foundation of specialty areas in criminology. List and discuss each of the three areas. In order to discuss the founding areas of Sutherland’s definition of crime, I’ll paste the definition as it is. "Criminality is a probabilistic event determined by the frequency and quality of interaction with persons holding definitions favorable or unfavorable to violation of the law." According to this definition â€Å"Criminality is a probabilistic approach†, something that describes the probability of committing a crime, something that is not instinctive but occurs with a potential threat in the society or a matter of self tolerance. â€Å"Probabilistic event†, explains that nothing can be proven with a 100% guarantee. In an experiment carried on 10 people to determine how many out of those 10 commit crime when exposed to a potential threat, if the ratio turns out to b e 51%, the probable explanation of the theorist is proved and hence the theory as well. â€Å"Frequency and quality of interaction with persons holding definitions favorable or unfavorable to violation of the law†; this factor of the statement describes the possible root of committing a crime, a proposed tendency to adopt criminal thoughts or criminal approaches if the person has more interaction with people who are involved in such acts, the depth or strength of the relationship with such people. Q. Discuss the importance of theory. Your answer should include the aspects and fundamental issues of theories. The most important thought that this theory puts forward is the fact, that a person is not born with a tendency to commit a crime. Biological factors might only have a 50% effect on a man’s nature but his social inclination towards people who have a history or background of crime increases a man’s potential to commit a crime. Social or civil discrimination or other such factors are also the reasons which cause a rise in criminal activities. Q. Define "cause". Theorist always present words in a way that don’t really present the fixation of their thoughts. ‘Cause’ of a possible crime can be explained by playing with words, providing general interpretations of what could be the possible factors. A ‘cause’ can be defined as a possible reason or a factor that may provoke a potential crime. Q. List and briefly discuss four of the definitional problems in defining crime. The first definitional problem in defining crime is its failure to specify it with determinance. Explaining an act on probable grounds does give a ratio of high regard but it still isn’t 100% guaranteed. Secondly is the relationship between the frequency and the quality of the relationships between individuals. Both frequency and quality set to give an entirely different outlook to the behavior of attempt of crime. The favorable and unfa vorable definitions on the attempt of crime vary differently on different occasions; hence, it cannot be a standard to determine crime. Q. What is the difference between criminology and criminal justice? Criminology is described more as a behavioral or a social study that intends to describe the social causes of crime or the reaction to crimes. Criminal justice on the other hand, is the field that deals with the collective aspect of criminal policy making. Or in other words its

Friday, November 1, 2019

Class Dialogue Assignment Example | Topics and Well Written Essays - 250 words - 1

Class Dialogue - Assignment Example Libreria Editrice Vaticana: 6-10, and 244 Accessed Online from http://w2.vatican.va/content/francesco/en/apost_exhortations/documents/papa-francesco_esortazione-ap_20131124_evangelii-gaudium.html. As seen from the social settings that human beings are separated either by color or ethnicity, it is no surprise that Catholics are seen the same way by other religions. Christians have been ridiculed this leading to division. In context, the topic at hand is covered by this source as it projects the dimensions of faith and how such faith can be distorted given that other religions and some races within Christianity do not auger well with each other. Racism is the bias towards a certain race. The Catholic Church as been viewed as one among the foundations of Christianity. However, politics have been immersed in to the church with racial profiling of clergies and other service individuals segregated along these lines. In context, this source provides supporting dialogue confirming that racism as well as favoritism are particulars in Christianity and thus more perspectives of analyzing the church should be considered. This quote shows that the division among Christians continues to be the very reason that Christians are unable to live or co-exist peacefully. In nations ravaged by violence, the Christians are even in a worse situation as the lack of unity projects even further complications as to how to conquer the hardships. Racial profiling is a problem in the justice system as it is in the religious setting. Considering the crises in Egypt and Nigeria, religious wars and lack of cooperation among Christians has driven the bar of reconciliation further as terror rages on. For instance, the abduction of school girls in Nigeria by a terror militia shows that the racial and religious conflicts continue to rage due to division among the Christians as pointed out by the USCCB. Paul VI. (1975). Pope Francis’ Evangelii Gaudium. Libreria Editrice